Version-1 (July-August 2018)
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Aim The present study was aimed to assess the liver dysfunction among diabetic patients attending the rural teaching hospital. Objectives: To study the activity of serum aspartate aminotransferase (AST), serum alanine aminotransferase (ALT), Total bilirubin (TB), and serum alkaline phosphatase (ALP) in T2DM patients and compare it with that of standard healthy controls. Materials and Methods: The present study conducted at MNR medical college and hospital, Sangareddy, India. A total of 150 study subjects who are attending the diabetic clinic are involved in this study during the period from February 2018 to May 2018. An institutional ethical committee approved the present study. A total of 100 type 2 diabetic patients...........
Key words: Diabetes mellitus, Liver function tests, Alanine aminotransferase, Aspartate aminotransferase, Alkaline phosphatase, Total bilirubin..
[1]. World Health Organization Consultation. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications, Part 1: Diagnosis and classification of Diabetes Mellitus. Report of a WHO Consultation. Geneva: World Health Organization, 1999.
[2]. Kiran Kumar Akka, Pampareddy B. Kollur, S.M. Awanti, Nagababu Pyadala. Evaluation of thyroid profile among type 2 diabetic patients attending to Basaveswara Teaching and General Hospital, Kalaburagi, Karnataka. IAIM, 2017; 4(6): 181- 186.
[3]. Sarala Devi Tenepalli, Nagababu Pyadala. Assessment of Oxidative Stress among Type 2 Diabetes Mellitus Patients Attending in A Rural Teaching Hospital, Sangareddy. IOSR Journal of Biotechnology and Biochemistry (IOSR-JBB), 2016; 2(5): 24-27.
[4]. Nagababu Pyadala, Ravindra Reddy Bobbiti, Ragalikhith Kesamneni, Rajaneesh Borugadda, Ravi Kumar, B. N, R. Vijayaraghavan, Rathnagiri Polavarapu. Association of Glycosylated hemoglobin and Lipid profile levels among Type 2 diabetic patients in Sangareddy. Research Journal of Pharmaceutical, biological and chemical Sciences, 7(5): 2849.
[5]. Gavin N. Levinthal and Anthony S. Tavill: Liver Disease and Diabetes Mellitus. Clinical Diabetes 1999, 17 (2):85..
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Soap bars are ideally considered to be free of organisms based on their high alkalinity & salt levels and thus considered not as candidate for spoilage, but repeated incidences of off colours/spots reported over the past has lead to increase incidences of rejection. Thus, in this study 20 unbranded soap bars available in local markets of Mumbai suburbs were screened for the presence of moderately halophilic gram positive cocci with special reference to the lesser known Nesterenkonia species, an alkalophilic organism. Eight different media known to support alkalophilic and halophilic organisms used to assess the microbiological load, revealed growth of organisms within the range of 103 to 105cfu/g. 151 isolates were picked up as representative of Operational Taxonomical Unit (OTU) of which 65 isolates were identified to be gram positive cocci on the basis of their cultural, morphological and biochemical characters. Comparison of 16S rRNA gene sequences showed that 4 isolates were phylogenetically closely related to Nesterenkonia species. Thus, survival of an extremophile organism like Nesterenkonia within the soap bars require strict imposition of microbiological...........
[1]. Archibald L. K., et al. (1997) Serratia marcescens outbreak associated with extrinsic contamination of 1% chlorxylenol soap. Infect. Control Hosp. Epidemiol. 18:704–709.
[2]. Billing E. (1955) Studies on a Soap Tolerant Organism: a New Variety of Bacterium anitratum. J . gen. Microbiol. 13, 252-260.
[3]. Buffet-Bataillon S., et al. (2009) Outbreak of Serratia marcescens in a neonatal intensive care unit: contaminated unmedicated liquid soap and risk factors. J. Hosp. Infect. 72:17–22.
[4]. Carrie A. Zapka, Esther J. Campbell, Sheri L. Maxwell, Charles P. Gerba, Michael J. Dolan, James W. Arbogast, & David R. Macinga (2011) Bacterial Hand Contamination and Transfer after Use of Contaminated Bulk-Soap-Refillable Dispensers. Appl Environ Microbiol 77(9): 2898–2904.
[5]. Collins MD, PA Lawson, M Labrenz, BJ Tindall, N Weiss and P Hirsch, (2002) Nesterenkonia lacusekhoensis sp. nov., isolated from hypersaline Ekho lake, East Antartica and emended description of the genus Nesterenkonia. Int J Syst Evol Microbiol, 52: 1145 -1150..
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Worldwide emergence of new resistance mechanisms in constantly increasing infections of Multidrug Resistance (MDR) bacteria (such as Methicillin resistant Staphylococcus aureus (MRSA) and Salmonella) is generating a major problem in treatment or prevention of infection against these pathogens. Development of resistance reduces the effectiveness of antibiotics against them. Antibiotics are costly and also harm useful microbes of host body, thus there is a need to adopt drug-independent remedial strategies to defeat pathogens. Phage therapy has therefore been considered as one of the strongest alternatives to antibiotics. Host specific Bacteriophages naturally and specifically kill their host without disturbing the normal microbes of host organism also provides cost effective treatment..........
Key words: Multidrug resistance, phage therapy, Methicillin resistance Staphylococcus aureus (MRSA), Salmonella typhi, Bacteriophages, sewage, pathogens, plaque assay.
[1]. Arlet G, BarrettTJ, ButayeP, CloeckaertA, MulveyMR, and White DG (2006) Salmonella resistant to extended-spectrum cephalosporins: prevalence and epidemiology. Microbes Infect. 8:1945–1954.
[2]. Cohen ML (1994) Antimicrobial resistance: prognosis of public health. Trends in Microbiology. 2 (10): 422-425.
[3]. European Food Safety Authority (2004)The community summary report on trends and sources of zoonoses, zoonotic agents and antimicrobial resistance in the European Union in 2006. European Food Safety Authority, Parma, Italy.
[4]. Falconer SB, Brown ED (2009) New screens and targets in antibacterial drug discovery. Curr Opin Microbiol. 12 (5): 497-504.
[5]. Mirzaei and Nilsson (2015): Isolation of phages for phage therapy: A comparision of spot tests and efficiency of plating analysis for determination of host range and efficacy : PLOS/one 10(3)1371..
